The Centre over the years has isolated several species of vibrios from shrimp (Penaeids) and prawn (M. rosenbergii) culture systems in India. The species identified so far are Vibrio alginolyticus, V. harveyi, V. parahaemolyticus, V. cholerae, V. splendidus, V. vulnificus, V. mediterranei, V. proteolyticus, V. fluvialis and V. neries. Pathogenicity of V. alginolyticus and V. harveyi has been demonstrated in M. rosenbergii and F. indicus respectively. The numerical taxonomy of family Vibrionaceae, is of particular interest to the Centre. An active research programme is underway to develop cost effective immunodiagnostic for vibrios using polyclonal antisera. A continuous monitoring program is being undertaken to identify emerging antibiotic-resistant pathogens from shrimp culture systems.